Expressiveness of global coagulation parameters in dilutional coagulopathy
نویسندگان
چکیده
منابع مشابه
Expressiveness of global coagulation parameters in dilutional coagulopathy.
BACKGROUND Plasma-free volume replacement in haemorrhage often results in dilutional coagulopathy. Prothrombin time index (PTI) and activated partial thromboplastin time (aPTT) are used for monitoring haemostasis but have not yet been clinically evaluated. Our aim was to investigate the effects of haemodilution on the course of global coagulation tests and clotting factors (CFs). METHODS Bloo...
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Dilutional coagulopathy can be reversed with fibrinogen concentrate. Effects of different fibrinogen dosages on clot function are not defined; high doses may increase the risk of thromboemboembolism. This study investigated the effect of six fibrinogen dosages on coagulation profile and blood loss in coagulopathic pigs. Forty-two pigs underwent a 60% hemodilution (HD) with hydroxyethylstarch (H...
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Perioperative dilutional coagulopathy is a major coagulation disorder during adult and pediatric surgery. Although the main underlying mechanisms are comparable, data of the development and management of dilutional coagulopathy in children are scarce. Observational data showed that intraoperative coagulation disorders mainly based on complex disturbances of clot firmness including acquired fibr...
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sugammadex. They posed the question of whether sugammadex had played a role in the recovery of their patient and we would like to suggest that perhaps a recovery could have occurred in a dramatic way after 15–20 min with traditional anaphylaxis treatment, as occurred in our patient. However, in our case, the cardiovascular collapse was not so severe, cardiopulmonary resuscitation was not initia...
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BACKGROUND : On the basis of logistic benefits of colloids over crystalloids, the U.S. military selected Hextend for resuscitation of combat casualties in the field. We investigated the effects of resuscitation with this fluid, as well as other colloids, on coagulation and uncontrolled bleeding in rabbits subjected to a splenic injury. METHODS : Anesthetized male New Zealand white rabbits (3....
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 2010
ISSN: 0007-0912
DOI: 10.1093/bja/aeq199